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Evaluación de propiedades biológicas de una matríz polimérica de polietilenglicol, nanohidroxiapatita y puntos de carbono para regeneración ósea

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Mancipe Celis, Paola Andrea
Abstract (Spanish)
Éste trabajo tiene como objetivo la síntesis y evaluación biológica de scaffolds poliméricos a base de puntos de carbono embebidos en nanohidroxiapatita para la regeneración ósea. Para la caracterización de PC y nHA-PC se emplea espectrofotometría UV-Vis (emisión y absorción) y espectroscopia infrarroja por transformada de Fourier (FTIR) para el caso de PC, nHA, nHA-PC y PEG-nHA-PC. Se realizan pruebas de citotoxicidad en nHA, nHA-PC y PEG:nHA-PC con proporciones 80:20, 70:30 y 60:40, mediante ensayos MTT y azul tripán en líneas 3T3 y vero.
Abstract (English)
This work aims at the synthesis and biological evaluation of polymeric scaffolds based on carbon dots embedded in nanohydroxyapatite for bone regeneration. UV-Vis spectrophotometry (emission and absorption) and Fourier transform infrared spectroscopy (FTIR) are used to characterize PC, nHA, nHA-PC, and PEG-nHA-PC. Cytotoxicity tests are performed on nHA, nHA-PC, and PEG:nHA-PC with ratios of 80:20, 70:30, and 60:40, using MTT and trypan blue assays on 3T3 and vero cells.
Director

Advisors/Directors

Rodríguez Burbano, Diana Consuelo
Extent
42 páginas
URI: https://repositorio.escuelaing.edu.co/handle/001/3575
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BA - Trabajos Dirigidos de Biomédica
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