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Diseño y simulación de un filtro de células de tipo linfocitos T en un sistema de microfluidos
dc.contributor.author | Quiroga Torres, Daniel Alejandro. | |
dc.contributor.author | Montenegro Mendez, Cristian Martin. | |
dc.contributor.author | Leguizamón Forero, Ana María. | |
dc.date.accessioned | 2021-06-18T01:28:20Z | |
dc.date.accessioned | 2021-10-01T17:16:57Z | |
dc.date.available | 2021-06-18T01:28:20Z | |
dc.date.available | 2021-10-01T17:16:57Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1692-7273 | |
dc.identifier.uri | https://repositorio.escuelaing.edu.co/handle/001/1583 | |
dc.description.abstract | Este trabajo consistió en diseñar y validar, mediante simulación experimental por computadora, un sistema de filtraje de linfocitos T en un sistema basado en microfluidos para detección del virus del vih. Materiales y métodos: se utilizó la herramienta de simulación AutoDesk® Inventor, con la cual se realizó el diseño del sistema de microfluídica. El sistema de filtraje se probó haciendo una simulación por computadora en la herramienta de simulación AutoDesk ® Simulation cfd (computational fluid dynamics software) en la cual diferentes partículas con varios diámetros (5 µm, 10 µm, 15 µm) fluían por el sistema a probar. Resultados y conclusiones: los resultados demostraron que el sistema de filtraje permitió el paso de las partículas esperadas, sin embargo, se observó que permitió el paso de partículas más grandes que las deseadas, por lo cual hay que seguir trabajando en el perfeccionamiento del sistema. La eficiencia del sistema de filtraje fue de un 33,33%. | spa |
dc.description.abstract | This work consisted in the design and validation, by means of experimental computer simulation, of a T lymphocyte filtering system in a microfluidic-based system for the detection of the virus, a T lymphocyte filtering system in a microfluidic-based system for hiv virus detection. virus detection. Materials and methods: the AutoDesk® Inventor simulation tool was used to design the system. was used to design the microfluidic system. The filtration system was tested by performing a computer simulation simulation tool AutoDesk® Simulation cfd (computational fluid dynamics software), which was used to design the microfluidic system. (computational fluid dynamics software) in which different particles with various diameters (5 µm, 10 µm, 10 µm, 10 µm, 10 µm, 10 µm and 10 µm) were (5 µm, 10 µm, 15 µm) flowed through the system to be tested. Results and Conclusions: The results showed that the filtration system allowed the passage of the expected particles, however, it was observed that it allowed the passage of particles with various diameters (5 µm, 10 µm, 15 µm) through the system to be tested, However, it was observed that it allowed the passage of larger particles than the desired ones, so it is necessary to continue working on the improvement of the system. system must continue to be improved. The efficiency of the filtering system was 33.33%. | spa |
dc.format.extent | 8 páginas | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | spa | spa |
dc.publisher | Universidad del Rosario | spa |
dc.source | https://revistas.urosario.edu.co/index.php/revsalud/article/view/4589 | spa |
dc.title | Diseño y simulación de un filtro de células de tipo linfocitos T en un sistema de microfluidos | spa |
dc.type | Artículo de revista | spa |
dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
oaire.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
dc.contributor.researchgroup | GiBiome | spa |
dc.identifier.doi | 10.12804/revsalud14.01.2016.02 | |
dc.identifier.url | http://dx.doi.org/10.12804/revsalud14.01.2016.02 | |
dc.publisher.place | Colombia | spa |
dc.relation.citationedition | Revista Ciencias de la salud : Vol. 14 Núm. 01 (2016) | spa |
dc.relation.citationendpage | 28 | spa |
dc.relation.citationissue | 1 | spa |
dc.relation.citationstartpage | 21 | spa |
dc.relation.citationvolume | 14 | spa |
dc.relation.indexed | N/A | spa |
dc.relation.ispartofjournal | Revista Ciencias de la Salud | spa |
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dc.relation.references | Katz MH, Komarov L. HIV Infection & AIDS. In: Papadakis MA, McPhee SJ, Rabow MW. eds. Current Medical Diagnosis & Treatment 2015. New York, NY: McGraw-Hill; 2014 | spa |
dc.relation.references | Unicef. hiv diagnosis: a guide for selecting rapid diagnostic test (rdt) kits. Copenhagen: Unicef; 2008 | spa |
dc.relation.references | Montenegro C., Leguizamón A., Quiroga D., Rojas C. Design, simulation and characterization of microfluidic system for human immunodeficiency virus detection. Health Care Exchanges (pahce). 2013;29:1-6. | spa |
dc.relation.references | Inglis W, Herman, N, Vesey, G. Highly accurate deterministic lateral displacement device and its application to purification of fungal spores. Biomicrofluidics. 2010;4(2),24109:1-8 | spa |
dc.relation.references | Gartner LP, Hiatt JL. Histología Texto y Atlas. 5.a ed. Chile: Mcgraw-Hill; 2011. | spa |
dc.relation.references | Autodesk. Autodesk Simulation cfd. [internet]. 2013 [citado 2015 ago 8]. Disponible en: http://www. autodesk.com/products/simulation-cfd/overview | spa |
dc.relation.references | Axel RP, Timothy WS. Blood Flow in Microvascular Networks, In Microcirculation. 3.a ed. San Diego: Academic Press; 2008. | spa |
dc.relation.references | Quan Guo, Simon P. Duffy, Kerryn Matthews, Aline T. Santoso, Mark D. Scott, Hongshen Ma. Microfluidic analysis of red blood cell deformability. Biomechanics. 2014;47(8):1767-76. | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.subject.armarc | HTLV (Virus) - VIH | |
dc.subject.armarc | Enfermedades - Medicina | |
dc.subject.armarc | Fluid dynamics | eng |
dc.subject.armarc | Dinámica de fluidos | spa |
dc.subject.armarc | Simulación por computadores | spa |
dc.subject.armarc | Computer simulation | eng |
dc.subject.armarc | Métodos de simulación | spa |
dc.subject.armarc | Simulation methods | eng |
dc.subject.proposal | Microfluidos | spa |
dc.subject.proposal | Sistema de filtraje | spa |
dc.subject.proposal | Virus de Inmunodeficiencia Humana (vih). | spa |
dc.subject.proposal | Filtration system | spa |
dc.subject.proposal | Microfluidics | eng |
dc.subject.proposal | Human Immunodeficiency Virus (hiv). | eng |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | spa |
dc.type.content | Text | spa |
dc.type.driver | info:eu-repo/semantics/article | spa |
dc.type.redcol | http://purl.org/redcol/resource_type/ART | spa |
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Clasificación: A - Convocatoria 2018